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Mezcal Margarita

Difford’s Guide
Discerning Drinkers (341)
Measurements in:
Serves:
1
Ingredients
1 12 fl oz Del Maguey Vida Clásico Mezcal
34 fl oz Cointreau L'Unique triple sec liqueur
34 fl oz Lime juice (freshly squeezed)
16 fl oz Agave syrup (agave nectar)
2 drop Saline solution (20g sea salt to 80g water) or merest pinch of s
8 drop Difford's Margarita Bitters (optional)

How to make

Glass

Photographed in an Everest Rocks Glass 12oz / 355ml

Prepare

  1. Select and pre-chill an OLD-FASHIONED GLASS.
  2. Prepare garnish of lime wedge.

Method

  1. SHAKE all ingredients with ice.
  2. FINE STRAIN into ice-filled glass.

Garnish

  1. Garnish with lime wedge.

Flavour Profile

No alcohol
Medium
Boozy
Sweet
Medium
Dry/sour

Health & Nutrition

Nutrition:

One serving of Mezcal Margarita contains 163 calories

Alcohol content:

  • 1.6 standard drinks
  • 21.59% alc./vol. (43.19° proof)
  • 22.1 grams of pure alcohol

Review

A smokin' Margarita. Depending on your palate, you may want to vary the amount of agave syrup – from 2.5ml or even no agave syrup for dry palates to as much as 7.5ml for sweeter palates.

AKA: Mezcalita

Cocktail of the day:

21st October 2026 is National Mezcal Day

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$4.07 per cocktail*

Makes a minimum of 16.5 cocktails.
Shipping and applicable tax calculated at checkout.


Orders are processed by a licensed Fulproof retailer. The buy now button is added simply for convenience.

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* May not include all ingredients. Price per cocktail is an estimate based on cost of one cocktail with ingredients shown above and does not include shipping.

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Comments & Discussion

Graeme McPherson
Last week my wife and I visited a New Mexican restaurant in our little town and I ordered one of their cocktails and “upgraded” the regular tequila to Mezcal. My first taste of Mezcal and I was hooked - similar to my first dalliance with peated scotch! My first mission this weekend was to find a bottle of Mezcal and the second mission was to head to Diffords to give me some pointers in the direction of some good recipes. And this Mezcal Margarita was no disappointment! A very well balanced drink with nuances of all the separate ingredients coming through on every sip. I made mine with Perro D San Juan and this might become my go-to margarita.
score: 1
Simon Bradley
I recommend a Mezcal Dante if you’ve not tried it yet. Really is one of the best cocktails on this site.
score: 2
Chris Dimal
Wow, this is the runner up for favourite Margarita ever. I still like it with a generous portion of a good, additive free Tequila Blanco more, but this is so good too. Perhaps more complex, I think because I used a decent Mezcal (Del Maguey San Luis del Rio). Smoke, agave, fruit and nice orange through the Triple Sec. One more thing is that I've experimented with putting a few dashes of lavender tincture (to kind of get some part of the Margarita Bitters character) and it really ties the whole thing together impeccably. Again, wish I could get those bitters.
score: 1
Florian Ruf Premium Member
John is absolutely right, i would suggest a not too smokey meszcal.
score: 1
John Hinojos Premium Member
Finding the correct Mezcal was critical for us. We have found other Mezcals a bit like drinking liquid smoke. Finally found a reposado Mezcal which is flavourful and with just hints of smoke.
This was a wonderful cocktail. Margarita Bitters always seems to soften and blend the tastes. Highest rating.
score: 1
Cassandra Adams Premium Member
Personally I find the sweetness from the triple sec enough, and so omitted the agave syrup. However, I tried to bring in the agave flavour by reducing the mezcal to half of that recommended and making it up with Almave non-alcoholic blue agave spirit. Could perhaps amend this to 3:1 in favour of mezcal next time, but I really enjoyed the result.
score: 2
Gabrielle14
Subbed lime for yuzu juice and turned out great!
score: 1
Mark
Way better than the classic margarita IMHO, smokiness adds an extra layer of complexity.
score: 1
Grey Goose
Very nice and refreshing. Used 2.5ml of honey instead of agave syrup and rimmed glass with tajin salt. Didn't have margarita bitters so used agnostura bitters instead which went nicely with the cointreau. May add a bit of soda next time to make it last longer as the drink finished too quickly!
score: 3
Rick Stark
GREAT Margarita.
score: 1
Kimberly Hynd
Wow!
This is a beautiful cocktail. The mezcal is perfectly balanced with the other flavors, delicious and smokey with nothing overpowered.
score: 1

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Difford’s Shop logo
$4.07 per cocktail*

Makes a minimum of 16.5 cocktails.
Shipping and applicable tax calculated at checkout.


Orders are processed by a licensed Fulproof retailer. The buy now button is added simply for convenience.

Checkout

* May not include all ingredients. Price per cocktail is an estimate based on cost of one cocktail with ingredients shown above and does not include shipping.