20 best Mezcal cocktails

Words by Simon Difford

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Mezcal is often used to add a touch of its distinctive character (often delicately smoky) to cocktails based on other spirits, particularly tequila. However, it's also great as the main spirit base, as many of the cocktails below illustrate.

1. Closing Argument


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With: Mezcal, Green Chartreuse liqueur, maraschino liqueur and lime juice.
We say: A mezcal-based Last Word. It works! End of argument.
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2. Division Bell


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With: Mezcal, bitter aperitivo liqueur, maraschino liqueur and lime juice.
We say: A mezcal-inspired variation of the Last Word with a refreshing, spirit-forward blend of ingredients.
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3. Dragon Punch


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With: Mezcal, Yellow Chartreuse, lime juice, orgeat syrup, and hot pepper sauce.
We say: An almond, mezcal and herbal liqueur Margarita with a touch of fire-breathing hot pepper sauce.
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4 Fire & Brimstone


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With: Red jalapeño, mezcal, triple sec, lemon juice, orange bitters and agave syrup.
We say: A refreshing riff on a Mezcal Margarita with enlivening chilli heat.
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5. Grasshopper No. 2


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With: White crème de menthe, white crème de cacao,
mezcal, fernet menta, absinthe, cream, and green food colour gel.
We say: A mezcal and amaro-influenced riff on the classic Grasshopper.
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6. Illegal Margarita


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With: Mezcal, Jamaican overproof white rum, falernum liqueur, maraschino liqueur, lime juice, sugar syrup, egg white, Margarita Bitters, and saline solution.
We say: Two massively flavoursome spirits and two very characterful liqueurs combine harmoniously in this delicious sour.
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7. Mezcal Dante


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With: Fresh basil, mezcal, blanco tequila, Green Chartreuse, kummel, agave syrup and lime juice.
We say: Some of the biggest flavours corralled, tamed and made to play together...
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8. Mezcal Margarita


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With: Mezcal, triple sec, lime juice, agave syrup, salt and Difford's Margarita Bitters.
We say: A smokin' Margarita.
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9. Mezcal Sour


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With: Mezcal, lemon juice, orange juice, sugar syrup, egg white, orange bitters, and saline solution.
We say: "Stone" in this mezcal sour refers to the inclusion of a splash of orange juice. It's delicious!
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10. Mezcal Stone Sour


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With: Mezcal, lemon juice, orange juice, sugar syrup, egg white, orange bitters, and saline solution.
We say: "Stone" in this mezcal sour refers to the inclusion of a splash or orange juice.
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11. Mezcalita


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With: Mezcal, triple sec liqueur, lime juice, orange juice, agave syrup, and Margarita Bitters.
We say: A Mezcal Margarita with a freshening splash of orange juice to accompany the triple sec orange liqueur that's essential to a proper Margarita.
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12. Naked & Famous


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With: Mezcal, bitter aperitivo liqueur, Yellow Chartreuse and lime juice.
We say: Mezcal adds earthy, smoky complexity to this bittersweet, citrusy, fresh aperitivo cocktail. Getting naked can help you become famous!
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13. Port of Spain (by Dominic Alling)


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With: Mezcal, orgeat syrup, lime juice and aromatic bitters.
We say: Named after Trinidad's capital city, the home of Angostura Bitters, this cocktail fittingly calls for a monster half an ounce of bitters.
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14. Smokin' Paloma


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With: Mezcal, pink grapefruit juice, lime juice, agave syrup, and pink grapefruit soda.
We say: Mezcal adds its distinctive flavours to a classic Paloma.
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15. Spicy Smoky Margarita


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With: Mezcal, triple sec, chili liqueur, lime juice and agave syrup.
We say: Just as it says on the tin, but delicately smoky and subtly spicy.
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16. Sunset Vibes


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With: Vodka, grapefruit juice, orange-red aperitivo, tonic water, mezcal.
We say: Appropriately coloured, this delivers a symphony of surprisingly harmonious sips.
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17. Tommy's Mezcal Margarita


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With: Mezcal, lime juice, agave syrup and Margarita Bitters.
We say: Depending on your mezcal and agave syrup, this can be delicately meaty with cleansing lime juice.
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18. Ultima Palabra


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With: Mezcal, Green Chartreuse, maraschino liqueur, pineapple juice and lime juice.
We say: Named after the direct Spanish translation of Last Word, hence the use of mezcal in place of the gin in a classic Last Word cocktail.
View the recipe


19. Velasco & Sand


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With: Mezcal, cherry brandy, rosso vermouth and orange juice.
We say: A mezcal-based Blood & Sand. Be sure to try this. It's better than the original.
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20. When The Smoke Cleared


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With: Mezcal, bitter aperitivo liqueur, ginger syrup, lime juice, pineapple juice and saline solution.
We say: Smoky, tangy and complex with layers of flavour, although happily mezcal dominates.
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